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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd026248e7e486d8505fd716e9db1e85d1c1fe846652d5e75cd7d094560cb64d' 
  AND token = 'aY2g8Oaut5DEkmFcE/JsUlmzeThDhoWeusLB6GxjVgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}