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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c485a790327636c8d753aad14b0b3323810d5a22fef8648dbf626b02c645eec' 
  AND token = 'gfUM+NjRrKnAWpsDwSmr+pUe4IYHpe0MEngj3Uvh2gA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}