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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d5c9bd184d7973f85c6d6721794d462f36d4f020267ebbda794a8a56d67eff' 
  AND token = 'kgJyezzUnxHsXNyDH/8uFbMef0ba/or0YvjDqXf4+TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}