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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60e621c836d5234e5a62950916f0b58cd993900103f8778e72ee6b2bcca9c18' 
  AND token = 'li+224Hlc9WSIMAXbgekCaD/vAXmcjwm7fwL+OQ1YV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}