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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5ed85591c56e758b8d7f1cfb14fdaded03c40759a5a614bc701e5917e3dab3' 
  AND token = '4uWRZBuoRDCyeoImPPCrbEtUGH0HFIkUyp5ETiGf5V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}