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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e5b86a3545fcfa23aa4a70a22123a81d1ee648ba1e8e91b0e5050af9a96a37' 
  AND token = '+ohq1qjSH5FmBwogSe8s4rJe2ztx5Z3YVf21G+Cuw1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}