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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374644224d3a2ae93065a2947aa75ce0ba48d1741711b011e6f2d7e491cf0995' 
  AND token = 'n3xOQqUfBVUtc9rGIV89qsWh7qSttSfZaBsU1+njJkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}