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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3107405253bb0d6ca5a997875c19044dd9ef9ec352f05ff14a2a579e1e88c483' 
  AND token = 'IwcCwIn4MuhtUtHpnkaX2vECloDlz5jdK40+QH+X1Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}