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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65a3d1f18c3e89adbedc15f00eb626d41ed64128b37d5e9a95ee115cb7de4fb' 
  AND token = 'zxqs0lsQtwxCww0l0ecrPwX+t+5ZE2UxF2HmDMZvKBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}