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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65b854c5770d0a17d3bc5a50a5f31f6911394887ddc7bafa63b78df545e49dc' 
  AND token = 'Ch+DVR7jSC76EaXcL9piO1gxcUvGuvoWBp3A/s4vx5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}