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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab64a3f2b69e80bf72b0206db59ea9c41324de9256c113fff15071b88497aea4' 
  AND token = 'c/SejA1DeeuMUI0A9qOMrK7ddahi5EiwbV1OWLHPQko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}