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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ba939b072d0dc3febeb762b0fc35f34c5a4b843df94fa71d57fc244c84e443' 
  AND token = 'UQvmNMXRO+8+32aCgvjx9FsUdLSBvaA9BvAAgQaE6TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}