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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2198b4a8df1d8aa50b674c012744254b153e7f426c0ba40f353078a8be53fc66' 
  AND token = 'RJKm9mI0a5oML0PNsz0CY5bvylIQMimjRIYGeD3hisw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}