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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7043c1b96ddd7ecb9101fdb82e7e95b05568b02d49ae70fccb85d48bcc3387' 
  AND token = 'JBXQzRxu4mXO/pKz9nclIjRYD064tGqjnx7zV8SVX70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}