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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47246efa3be3897e9987225226ca2a4aa691c2568c9376226746af2d07db069f' 
  AND token = 'v5UC5HMdFBfNdX+XKa3ddsccYkQTsTdBL4H0kLJWhFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}