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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '079b1a7ee858a35f0d6c6e2fcac0e2d0521d110cae9d21f3a6a50c92663d0206' 
  AND token = 'xZWCG08VFGd7BfXdmjDjqYJCcymxUt/cWpPTHrIdvqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}