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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca3556c5e3264deee01499998aa885775fe1c12b40bfc10e23fbb9fcb8b406f' 
  AND token = 'jhSqNNv/WH5VmOAD/N53DeLX5ve+gDYa+0RTKHYYR/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}