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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8801f571acbd28e1211362dfc516392404f6f4f65f57fdb41c9dc7a5f0ea0d' 
  AND token = 'c+HCCrfFY/W7Wcx3GhXoelEK8m5+cZVuIRlrStTzLCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}