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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b3d6c702aacdcdc7af1b4e438065cdda729cb217d39a4950fa80a1a2767c7a4' 
  AND token = 'X/Se+aF7W2vWdYml4aKAKxKkyeH/FZ01YUf34fdTuaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}