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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef183cd802280baaa097b790adf29198973d3f19efafdffcb167c072f83102e5' 
  AND token = '4PGUEVwNE41tN01gZ1Bj//G1q4ZVOoBu8D+i+5bIxsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}