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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '611a81f2820b9939c9209682da5529ffe2a77a7618880a10e4478599e6e36bd2' 
  AND token = 's2xrJm/C9e8gpM0OABaYbrkYebLogFh2mGAuJo18kAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}