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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf216ee2f97edd76d03defd3d997845158e8f24ded8022690afb60bf02dc155f' 
  AND token = 'R3mTkwYINr+F4lpq0OnLPeeulLLv1zB3zSPPvoi5fpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}