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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10cc38c35dcc107c4d2af586149d172a0724e80f8e5ff41b6a5097ad5cc44a3b' 
  AND token = 'CaU13nDfQ5JmSu9+m1bPl9LsOexiXCKKLxb7exmPLFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}