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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86630b8a94a84d95e96ad3c830261a3f08e39de3d727b357c3f55a55b8e23989' 
  AND token = '2HmqJ+y7mZNWXgKQ0Z1582HBVBmLePINy/iC85u3t3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}