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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed186e61c559cbac0d807030fd889c3d69d5d054cb8b37e7e06d7cc648b45473' 
  AND token = 'yf3sWfyyeit/CUxASCeRyfHFNMP7suko3D0ojRXXh4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}