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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4337058cf50d1d2f1e8f6d49a88684831b5e633458f6b601b7fd4d1a42c35eed' 
  AND token = '+AfFz4rVeWhj0e33g8yNkkPueH3MajqqPYCb2/y7M78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}