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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b6d2c5d44cfd54c801b566c3d510fdd1d4049a9ab472363516029c327e405c' 
  AND token = 'e0aYW3VUnhO6SwQbvGyHu3EfZ0sJ8lLrQ7C6dmckxuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}