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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d152133a5c4487317fcd763b72f8e069899e750331fee955e9b0e67611d58fc' 
  AND token = 'YdImXkhg+rVMfCgAcR1AWe+itilytQXqFxwDX2y2k5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}