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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fcb5563c81feabbdcff9be5c32b53dac3f93c4f436286b343b4a9b5fcd4e9a9' 
  AND token = 'VZdKa9DSNRemm/gY2BKAXqIKAWZJc90WjqPtlSsxAqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}