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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed48504850a7df74d4fa959c03708137252c48c714560dd5981ca8c0d4c0606' 
  AND token = 'v7WrL8vxrMwunHzgtiv4f6pQ4wiFTEc8hnRCT7vw2AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}