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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b770b693ba893255723d0335f89ba0785cf950b2089a180e0d39c7eb2c6ad1b' 
  AND token = 'JSFl9lgyPqNZ3x0KxkWoyco3meMGJ4jJP+kM4hSxxLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}