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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216229582ad567903755bf7fac854a38b367f1f930190771875ca3e9579668a3' 
  AND token = '0Bb+MGgV9D41dCFYHuMkkNnsxDS3tTFfiYx164Os4y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}