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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b4d19f6bb8358fc0a04e0873e6738999627d3e7be319d05cb64864d56d6afa' 
  AND token = 'rlY5L6AYwdgh9LXUz2nI7n9mptenr6l4ShTWqJl+EmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}