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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85c83cc1776035b107363563cd8dd74f0830321f4aad9d8691bd69a78c51b280' 
  AND token = '+RqD/4EA92Yo8iEVuKf063/CSDJY2vTBIbZQVxdqL0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}