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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abcde7b34d2b777c9d6429853315659dca112ff1bb5e2afca3fd380c3be358b4' 
  AND token = 'DZTbvJ5eROz0nM49rOziDVE2gFUg7z2AKHX5JvS4pFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}