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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39fb25a0d1596907f4c7ead567ae2b22fc0416573075e0ecff8e557922dfa65a' 
  AND token = 'z8fajpKPFJlvdK1/WgBSFlcFInp0c0rOR2qAetd/AZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}