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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1506ebd15e89c84a39f5d83469c0f281efcc5e1ffbc3218eb3db6f20c6fad17a' 
  AND token = 'sCU5+d56/aabnYXc1FPVUwTB7ZcYLnfDjgaxG49VQXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}