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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d668368c494c3539621695b59f8eafa74e4d3fe9db6554ef5515074f3a32542' 
  AND token = 'PFyNNa6S3I5aFzbpegl1EUfM1PYhVd0gDfCvPmFTHP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}