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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c7b487b6bfafc15b613126d34c7ea5ff6a6d3b01d2f2222dbe37cbce2ee379' 
  AND token = '+X0HlIFAA+wRSoIvW3+MDX8/okIWO05rOxHlbFK/T3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}