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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c8d466331e28c4e8af2d5832c2410b0d2115c5c3f08892e5d27bce2d59d660' 
  AND token = 'Htaj3piSBtAnKa+k9yaHSJkyrO5PUjzzadSDfQqx4Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}