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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae0d6053901d28714c941da00e3566c5c08ffb648382787544b7fe694d600d6' 
  AND token = 'VHaRcscw8YXm2iQ7uToSMZHtNUvt+BQZ1HMuZ/u53EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}