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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aeeeeb344d7c382a4f1cca921f798b33679b1d130ed22b80965f83fc7acbfb1' 
  AND token = 'zpZ4uHH33nGHUEiinHFptjhQQ9+e0G9aAfmhNPj8gUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}