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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3386eecc5aa4ae3553db92c20a5c39f5ef06c42c17cf031ff8df21a4d27118a' 
  AND token = 'pO1hPCTD6dD08zBXOAcZIAL7d8TPcdjPDEved+NZ6vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}