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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95209e7d7094420785bde91611c32d75992398c714d8da903b75e7f25888b0c2' 
  AND token = 'LVO/P0Zut4/EWVLkgJv3oKYTDW/FUqPCPZQcEZ3EFDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}