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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f555676c438a57c017c59ab99e9ebd1eab5901fd20a961889b1ea741f043dd4' 
  AND token = 'VLXNRJ4bUwOYwZNFA1AqV3+F00VhF6CcXDGkvHPWXkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}