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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b59ea3cbaf5a4f2cc17b6e2b37d27faa5e2abffb95b1d84fcdfca0b8359fee' 
  AND token = 'oDK6igaB2x3QTLK9a+C4tcZgOKjwgWbHOI9Hp/NWlc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}