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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1736893725c642839846383c78a70c6b5e7307a3cc6e744e8b2b30f124e9c3' 
  AND token = 'GcjFRTqzsfbDfwSqTUCIER4fJKMFMWZ8TcFrtAQg3vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}