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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0a624d2d9b41921579d3a944c09e9b7e651040324fdfa589b24d554724fd87' 
  AND token = 'crXb3Eak6FTsrWuu8/HEJLaGpqollXNZE4vJnhlIqnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}