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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a61ea8a6c73bba90157820db752608c51d7ee99a727e7c85c64888ea645549' 
  AND token = 'QMxdLAMmzdQcfk/m+ZoPWSevi+rxfdM2xXAEDcmZa5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}