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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82fb1844e41fcf36a3ff25d7f95092defcfd22099b7df00ca21fe90029682549' 
  AND token = 'R1J5wT3R2OUM+KBPc29s3eNORUbKqqxPl9B8pkqOVOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}